Influence of smoking and diet on glycated haemoglobin and ‘pre-diabetes’
نویسندگان
چکیده
3 Antonis Vlassopoulos MSc, Mike EJ Lean Prof* and Emilie Combet PhD 4 Human Nutrition, School of Medicine, College of Medical, Veterinary & Life Sciences, 5 University of Glasgow , Glasgow, G3 8SJ, UK 6 7 Antonis Vlassopoulos: Human Nutrition, Yorkhill Hospital, School of Medicine, College of 8 Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow. 9 Email:[email protected] 10 11 Emilie Combet: Human Nutrition, Yorkhill Hospital, School of Medicine, College of 12 Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow. 13 Email: [email protected] 14 15 *Corresponding Author: Professor Mike Lean, Human Nutrition, Walton Building level 4, 16 Glasgow Royal Infirmary, School of Medicine, College of Medical, Veterinary and Life 17 sciences, University of Glasgow, Glasgow. Tel +44 141 211 4686, Fax: +44(0)141 211 4844, 18 E-mail: [email protected] 19 This study was funded through a scholarship from the Yorkhill Children’s’ Foundation 20
منابع مشابه
Influence of smoking and diet on glycated haemoglobin and 'pre-diabetes’ categorisation: a cross-sectional analysis
BACKGROUND The new HbA1c criteria for diagnosis of pre-diabetes have been criticised for misdiagnosis. It is possible that some elevation of HbA1c is not driven by hyperglycaemia. This study assesses associations of HbA1c, commonly assumed to relate solely to glucose concentration, with (i) smoking, a major source of reactive oxygen species (ROS) and (ii) fruit & vegetables consumption associat...
متن کاملGlucose Influence on Copper Ion-Dependent Oxidation of Low Density Lipoprotein
Background: It is well established that oxidative modification of low density lipoprotein (LDL) plays a causal role in human atherogenesis and the risk of atherosclerosis is increased in patients with diabetes mellitus. We examined the in vitro effect of glucose on native and glycated LDL oxidation using copper ion dependent oxidation system. Methods: In this study, LDL was isolated from plasma...
متن کاملHigh awareness of diabetes in the health care system in Greenland measured as a proportion of population tested with glycated haemoglobin within 2 years
BACKGROUND Sixty years ago diabetes was almost non-existent in Greenland and until the beginning of this century awareness of diabetes was quite minimal. A high prevalence of undiagnosed diabetes has been reported in repeated population surveys. Increased focus on diabetes has been made a priority within the health care system since 2008, and in 2010 glycated haemoglobin was introduced as a dia...
متن کاملThe Effects of Plant-Derived Oleanolic Acid on Selected Parameters of Glucose Homeostasis in a Diet-Induced Pre-Diabetic Rat Model.
Prolonged exposure to high energy diets has been implicated in the development of pre-diabetes, a long-lasting condition that precedes type 2 diabetes mellitus (T2DM). A combination of pharmacological and dietary interventions is used to prevent the progression of pre-diabetes to T2DM. However, poor patient compliance leads to negligence of the dietary intervention and thus reduced drug efficie...
متن کاملIndependent Associations of Fasting Insulin, Glucose, and Glycated Haemoglobin with Stroke and Coronary Heart Disease in Older Women
BACKGROUND Evidence suggests that variations in fasting glucose and insulin amongst those without frank type 2 diabetes mellitus are important determinants of cardiovascular disease. However, the relative importance of variations in fasting insulin, glucose, and glycated haemoglobin as risk factors for cardiovascular disease in women without diabetes is unclear. Our aim was to determine the ind...
متن کامل